What Is Priligy, How It Works and How to Take?

Priligy is a pharmaceutical with the active principle dapoxetine that was developed and tested as an antidepressant. It proved to be too fast-acting and too quickly metabolized when used for depression, but it turned out to be very effective in preventing premature ejaculation.

For most living creatures, sex is only there for procreation, and the more quickly it can be over, the less they expose themselves to threats from predators while they are otherwise occupied. But humans have turned sex into an art and a pleasurable activity. And because we enjoy it so much, we not only want to last long enough to give pleasure to our partners but also be able to take our time to maximize our own pleasure.


But there’s a serpent in the garden of earthly delights: premature ejaculation. In severe cases, men may even ejaculate before being able to initiate sex. In others, ejaculation follows shortly after penetration. This is frustrating for men and their partners, and until quite recently, they just had to live with it!

What Is Priligy?

So, what is Priligy and what makes it unique?

Priligy is a pharmaceutical with the active principle dapoxetine that was developed and tested as an antidepressant. It proved to be too fast-acting and too quickly metabolized when used for depression, but it turned out to be very effective in preventing premature ejaculation.

It is the first drug of its kind, representing an important achievement in the men’s health arena. Since its launch, men suffering from premature ejaculation (PE) have been able to enjoy a normal sex life – unless they happen to live in the US.

The FDA has been dragging its feet in the approval process, even though Priligy is available almost everywhere else in the world since the early 2000s. In this time, it has proven itself to be both safe and effective, and the FDA is set to approve its use in the US “soon.” How soon this may remain unknown.

What Is It Used For?

Priligy (dapoxetine) is exclusively used to delay ejaculation in men who suffer from PE. To date, no other use has been revealed, but as the first drug ever made available specifically for this use, it has been hailed as a breakthrough.

How Does Priligy Work?

Priligy’s mechanism of action is based on its ability to increase serotonin in the body. It limits the reuptake of serotonin and is thus a serotonin reuptake inhibitor (SSRI). Researchers theorize that Priligy works by relieving the emotional stress that often causes PE. As a result, other drugs in the dapoxetine family (SSRIs) have been prescribed off-label, but these are less helpful and can be harmful.

To be effective, other SSRI drugs have to be taken every day, whereas Priligy can be used sporadically as needed. Taking SSRIs other than Priligy daily increases the risk of side-effects and ironically, this can cause loss of libido or even erectile dysfunction. Priligy doesn’t have this drawback. Because the body processes it quickly, it doesn’t build up in the system.

How Long Does It Last?

The onset of action occurs in about one hour, but you can wait up to three hours after using Priligy and still find it effective. For some men, it will last even longer. The best way to find out how dapoxetine works for you is to test it yourself. However, the official instructions are to use it one to three hours before intercourse.

Remember, before you find yourself regretting how long it lasts, this drug was specifically chosen because it metabolizes quickly. That’s what makes it so safe.

How to Take This Drug

Men can take 30mg to 60mg of dapoxetine to three hours before they expect to have sex to solve the problem of PE and last longer. Most men find that 30mg is enough to work, but one pharmaceutical trial found that Priligy 60mg doses resulted in a longer period between penetration and orgasm than a 30mg dose. However, it also found that this higher dose only resulted in a further extended pre-ejaculation time in men who have lifelong PE.

When Is the Best Time to Take Priligy?

Unless you have sex daily, there is no real point in taking Priligy daily, and ideally, you should take time off your Priligy at intervals. Although some men may find the one to a three-hour window in which it is effective frustrating, Priligy would be subject to the same side effects as other SSRIs if it had a longer-lasting action. And who wants to lose their libido?

How Safe Is Priligy?

Priligy is one of the safest drugs on the market today. Very few people suffer from side-effects, and there are no dangerous ones. If you are one of the few people who find that Priligy doesn’t agree with them, it will be because you had a headache, dizziness, diarrhea, trouble sleeping, or a dry mouth.

When medicines make us feel uncomfortable, we stop taking them. Here’s what researchers found when investigating what percentage of men discontinue Priligy:

Drug and Dose % Discontinued
Placebo 0.3
Dapoxetine 30mg 1.7
Dapoxetine 60mg 5.3

There is no record of anyone having overdosed on this drug, but as we can see from the above, higher doses increase the risk of side-effects that could force you to quit using Priligy. However, it’s worth noting that even the 5.3 percent of people quitting Priligy owing to side effects at relatively high doses is still an extremely small proportion for any pharmaceutical.

Who Should Not Use Priligy?

There are two issues that need to be considered here: what health conditions preclude the use of dapoxetine or Priligy, and what medicines could it interact with?

Health conditions that mean you shouldn’t use Priligy:

  • liver disease or reduced liver function;
  • ischemic heart disease.

Drugs with which Priligy should not be combined:

  • CYP3A4 inhibitors (example ritonavir, telithromycin, ketoconazole);
  • other SSRIs (these will be anti-depressants);
  • Tricyclic antidepressants;
  • Serotonin-norepinephrine reuptake inhibitors;
  • Monoamine oxidase inhibitors;
  • Thioridazine.

If your doctor wants to prescribe any of these drugs for you, you will first have to wait one week before you begin using them. When you stop using these medications, you will have to wait two weeks before you can use Priligy again.

How to Get Priligy Online

How to get Priligy online is a simple enough matter. In fact, it’s really the only way for men in the US to get it at all. Regretfully, you will need to be careful about the online pharmacy you choose. You are quite likely to get a placebo (or no delivery whatsoever) from some dishonest online pharmacies. That’s why getting samples is a good idea.

You should also investigate the reputation of the pharmacy. You may be sure that if it does not offer genuine meds, there will be complaints. Men who buy medication such as this based on false promises of its effectiveness will be quick to trash the online reputation of a business that cheated them.

Fortunately, it’s not all doom and gloom. Countless men rely on online pharmacies for drugs such as Priligy and receive excellent service.

Is it legal? Technically, no. At the same time, this is not a narcotic or other banned substance, so it falls into an interesting gray area. If customs services notice that you are importing tablets, they will seize them and send you a notification letter. If you don’t respond to that letter, you won’t hear from them again.

The Only Proven Solution for PE

A look around the internet will uncover myths, legends and folk remedies galore. It seems as if a great many people are trying to profit from the misfortune of those living with PE. Also, there is a combined drug Viagra plus dapoxetine called Super P Force. You may research as many reputable sources as you can find, and you’ll find they all agree: Priligy is the ONLY drug to enjoy widespread acceptance in the scientific community as a treatment for PE.

Since many of the snake-oil salesmen will specifically list the side-effects of the other SSRIs, falsely claiming that Priligy will cause loss of libido and erectile dysfunction, you are also welcome to check mainstream sources regarding Priligy safety and longer-term effects.  You will find that the information presented here is completely correct. After all, our clients’ health is important to us!

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